To ensure that biotechnologically produced drugs are not recognized as foreign by the immune system and eliminated prematurely from the body, biotechnology uses different methods for modifying them so that effective drug delivery is possible.
celares gmbh is specialized in modifying biopharmaceuticals with polyethylene glycols (PEG), through which active ingredients have a longer effect in the body and are more soluble. Whereas in this technology the ingredients are chemically coupled with PEG, Alrise Biosystems GmbH encapsulates biotechnological ingredients with a microparticle envelope. This envelope prevents the drugs from decomposing in the liver, but instead allows them to be released in a controlled manner into the body.
The above technologies not only reduce side effects; the drugs also need to be taken less frequently.
Drug delivery is not only interesting for newly developed substances: Biopharmaceuticals already on the market can gain new patent protection with the aid of a new form of administration.
Eckert & Ziegler Wins Order for Hot Cell Construction from Dutch Research Center
Eckert & Ziegler has been awarded a contract to build hot cells with a value of several million euros. The order was placed by the Nuclear Research and Consultancy Group (NRG) in Petten (NL), a global...more ...
Eckert & Ziegler: Seed Implantation for Prostate Cancer Receives Reimbursement for Outpatient Care
Seed implantation for prostate cancer is now to be reimbursed as an outpatient treatment by public health insurances in Germany. This was decided by the Federal Joint Committee (G-BA) with effect from...more ...
Single Mouse Trials: mimicking clinical phase II trials in PDX models with manageable costs and efforts
The long and successful collaboration of EPO Berlin-Buch GmbH with the Charité University Hospital in Berlin recently led to the following publicationmore ...
Pharmacokinetics - Essentials for Project Managers in Biotech Companies
Basics in understanding pharmacokinetics in clinicial development - for non-physiciansmore ...
GMP Biotech Summer School
Good Manufacturing Practice (GMP) Basic Course Biotechnology (English)more ...